Posttranslational Modifications of Tubulin and the Polarized Transport of Kinesin-1 in Neurons

摘要

During the development of neuronal polarity, the Kinesin-1 motor translocates preferentially to the axon. We show that Kinesin-1 selectivity does not depend on differences between axons and dendrites in microtubule stability or tubulin acetylation, but is likely specified by other tubulin posttranslational modifications.